William Thomas AstburyBorn 25 Feb 1898; died 4 Jun 1961 at age 63. English physical biochemist who was the first to make use of X-ray diffraction patterns to study the structure of nucleic acids (1937). Astbury researched the method under Bragg for seven years, then investigated the structure of wool in both the stretched and unstretched forms. From the difference in the diffraction patterns, he began to try to work ot the structure of protein molecules. His preliminary determination of the structure of nucleic acids were, in fact, wrong - but it gave impetus to Pauling's work with proteins, and to Crick and Watson's study of DNA structure. His work, slowly decoding the nature of molecular structure of virtually the largest organic materials, fibrous and globular proteins, was valuable to both science and industry. |
