Edmond H. FischerBorn 6 Apr 1920.American biochemist who shared (with Edwin G. Krebs) the 1992 Nobel Prize for Physiology or Medicine for the discovery of “reversible protein phosphorylation as a biological regulatory mechanism” which governs the activities of proteins in cells. They purified and characterized the first enzyme of this type. Their discovery was a key to unlocking how glycogen in the body breaks down into glucose. It fostered techniques that prevent the body from rejecting transplanted organs. Their breakthrough also opened new doors for research into cancer, blood pressure, inflammatory reactions and brain signals.« |