David KeilinBorn 21 Mar 1887; died 27 Feb 1963 at age 75.Russian-British biochemist who discovered cytochromes, as enzymes critical to the cell's use of oxygen (1923). His career began as an entomologist studying the life cycles of flies. While studying the absorption spectrum of the muscles of the horse botfly, that he noticed four absoption bands that disappeared when the cell suspension was shaken in air, but reappeared afterwards. He had found a respiratory enzyme. He named it cytochrome, and began a thorough investigation of its role in cellular respiration. Like haemoglobin, the cytochrome enzyme contains iron. Cytochrome is a pigment found in some cells, such as bacteria and yeast. He studied also catalase and peroxidase which are also iron-containing enzymes with a role involving oxygen. |
