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Replace the question mark with a number

MATH PUZZLE: Can you replace the question mark with a number?

Correct answers: 169

The first user who solved this task is H Tav.

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Same Patient

After I warned the nurse taking blood that it would be very hard to find a vein on me, she said, "Don't worry. We've seen worse. Last year we had a girl come in to get a blood test for her marriage license and we had to stick her six times in four places before we got anything."
"Yes, I know," I said. "That was me!"

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Ilya Prigogine

Born 25 Jan 1917; died 28 May 2003 at age 86. Russian-born Belgian physical chemist who received the Nobel Prize for Chemistry in 1977 for contributions to nonequilibrium thermodynamics, or how life could continue indefinitely in apparent defiance of the classical laws of physics. The main theme of Prigogine's work was the search for a better understanding of the role of time in the physical sciences and in biology. He attempted to reconcile a tendency in nature for disorder to increase (for statues to crumble or ice cubes to melt, as described in the second law of thermodynamics) with so-called "self-organisation", a countervailing tendency to create order from disorder (as seen in, for example, the formation of the complex proteins in a living creature from a mixture of simple molecules).

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