Hans BuchnerBorn 16 Dec 1850; died 5 Apr 1902 at age 51.Hans Ernst Angass Buchner was a German bacteriologist who discovered gamma globulins, natural bactericides carried in the blood, while making immunological studies in1886-90. He also devised methods of studying anaerobic bacteria. In 1891, Buchner proposed the existence of antibacterial proteins in blood serum which he called "alexines". This began a protracted debate with Metchnikoff, who championed a cellular theory of immunity. In 1893, he proposed that antitoxin formed directly from the toxin itself. With his brother, Eduard, in 1897, Hans demonstrated that completely dead yeast juice could ferment sugar, forming carbon dioxide and alcohol, exactly as the intact cells would have done. This presaged the description of enzyme activity. |
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