Sir Christopher WrenBorn 20 Oct 1632; died 25 Feb 1723 at age 90. English architect, mathematician and astronomer who was the greatest among the country's architects of his time. While at Wadham College, Oxford (1649), he joined a group of brilliant scholars, who later founded the Royal Society (president 1680-82). Wren learned scientific skills as an assistant to an eminent anatomist. Through astronomy, he developed skills in working models, diagrams and charting that proved useful when he entered architecture. After London's Great Fire of 1666, Wren presented a scheme to rebuild the city, though only partially realized. He designed many buildings including St. Paul's Cathedral and 53 churches. He invented a “weather clock” similar to a modern barometer, new engraving methods, and helped develop a blood transfusion technique. His scientific work was highly regarded by Sir Isaac Newton as stated in the Principia.