ThalidomideIn 1957, the notorious drug thalidomide was first marketed in West Germany and shortly sold in at least 46 countries. First synthesized in 1953 by Chemie Grünenthal, as a sedative, it seemed a wonder drug for pregnant women to combat symptoms associated with morning sickness. Too late it was found that the drug's molecules crossed the placental wall, especially during the first trimester, tragically affecting the proper growth of the foetus. Worldwide, over 10,000 babies were born by the early 1960's with substantial birth defects, including deafness, blindness, internal disabilities, cleft palate, deformed or even missing limbs. Survivors, now middle-aged adults, have continuing health problems. Yet, some beneficial uses have now been found for the drug.« |