“The Three Little Pigs order off the vegan menu, but Mary Had a Little Lamb.”
Sir Arthur HardenDied 17 Jun 1940 at age 74 (born 12 Oct 1865).English biochemist who shared (with Hans von Euler-Chelpin) the 1929 Nobel Prize for Chemistry for work on the fermentation of sugar and the enzyme action involved. Harden continued the work of Eduard Buchner who had discovered that such reactions can take place in the absence of living cells. Harden demonstrated that the activity of yeast enzymes included both large protein molecules and essential coenzymes - small nonprotein molecules. This was the first evidence for the existence of coenzymes. Harden also discovered that yeast enzymes are not broken down and lost with time, but that the gradual loss of activity with time can be reversed by the addition of phosphates, which are now known to play a vital part in biochemical reactions. |
