Hans SelyeDied 16 Oct 1982 at age 75 (born 26 Jan 1907). Hans Hugo Bruno Selye was an Austrian-born Canadian endocrinologist known for his studies of the effects of stress on the human body. Selye first detected the effects of stress in 1936 when he injected ovarian hormones into the glandular system of laboratory rats. The hormone stimulated the outer tissue of the adrenal glands of the rats, caused deterioration of the thymus gland, and produced ulcers and finally death. He further determined that these effects could be produced by administering virtually any toxic substance, by physical injury, or by environmental stress. In humans, Selye demonstrated that a stress induced breakdown of the hormonal system could lead to conditions, such as heart disease and high blood pressure, that he called "diseases of adaptation." |