Otto MeyerhofDied 6 Oct 1951 at age 67 (born 12 Apr 1884).Otto Fritz Meyerhof was a German biochemist and corecipient, with Archibald V. Hill, of the 1922 Nobel Prize for Physiology or Medicine for research on the chemical reactions of metabolism in muscle. In 1940 he emigrated to America. Meyerhof demonstrated that the production of lactic acid in muscle tissue, formed as a result of glycogen breakdown, was effected without the consumption of oxygen (i.e., anaerobically). The lactic acid was reconverted to glycogen through oxidation by molecular oxygen, during muscle rest. This line of research was continued by Gustav Embden and Carl and Gerty Cori who worked out in greater detail the steps by which glycogen is converted to lactic acid - the Embden-Meyerhof pathway. |
